گندله آهن: یک کاتالیست طبیعی و قابل بازیافت برای تهیه دی هیدروپیریمیدین ها در محیط آبی

نوع مقاله: کوتاه پژوهشی

نویسندگان

گروه شیمی، واحد کرمان، دانشگاه آزاد اسلامی، کرمان

چکیده

باتوجهبهاهمیتهتروسیکل ­های دی هیدرو پیریمیدین بهعنوان ترکیب ­های فعال زیستی و دارای اثرهای دارویی متنوع در شیمی و بیوشیمی، دراینپژوهش از گندله اهنبهعنوانیککاتالیست طبیعیناهمگنو قابلبازیافتبرایتهیهمشتق ­های 3، 4- دی هیدروپیریمیدینی باواکنشسهجزیی و تک مرحله ای  اتیل استو استات، اوره و انواع متفاوتی از آلدهیدهای آروماتیک درحلال آب و اتانول استفاده شد. ازبرتری­ های روشارایهشده می ­توان به بازده خوب فراوردده­ها،ارزان و طبیعی بودن کاتالیست، قابلیتاستفادهدوبارهکاتالیست و روش جداسازی و خالص سازی آسان اشاره کرد. استفاده از آب به عنوان محیط واکنش این فرایند را از نظر اقتصادیبه صرفه و از لحاظ زیست محیطی ارزشمند می­ سازد.

کلیدواژه‌ها

موضوعات


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