نشریه شیمی و مهندسی شیمی ایران

نشریه شیمی و مهندسی شیمی ایران

سنتز کرومن ها از مشتقات بنزیل الکل با استفاده از کاتالیست شیف باز کبالت (II) متصل به کرون اتر و نشانده شده بر روی نانو ذرات سلولز

نوع مقاله : علمی-پژوهشی

نویسنده
رضا سندروس
شیمی، دانشکده علوم، دانشگاه بیرجند، بیرجند، ایران
چکیده
در این پژوهش یک کاتالیست شیف-باز-کبالت (II) حاوی کرون اتر، تثبیت شده بر روی نانو ذرات سلولز (Crowned Imine-Co (II)@CNC) تهیه شد. این کاتالیست به وسیله تکنیک­ های SEM، IR، TGA،  XRD، EDX و TEM شناسایی گردید. این ترکیب به عنوان کاتالیست ناهمگن در سنتز پیش ماده­های دارویی کرومن، مورد استفاده قرار گرفت. کرومن­ ها با بازده خوب (%77 تا %99) و در طی یک زمان کوتاه 20 دقیقه از طریق واکنش بین دی­کتون­ ها، مالونونیتریل و مشتقات مختلف بنزیل الکل در حلال آب سنتز شدند. استفاده مجدد از کاتالیست بازیافتی (تا 4 مرتبه) تغییری در بازده واکنش ایجاد نکرد. وجه تمایز این روش با سایر روش‌های سنتز کرومن­ ها با استفاده از مشتقات بنزیل الکل بجای بنزآلدئید می ­باشد.
کلیدواژه‌ها
شیف باز
کرون اتر
نانوذرات سلولز
کرومن
بنزیل الکل

موضوعات

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