Nashrieh Shimi va Mohandesi Shimi Iran

Nashrieh Shimi va Mohandesi Shimi Iran

Synthesis of Benzo[b][1,4]oxazine-2-amines via the Multicomponent Reaction between Benzyl Alcohol, 2-aminophenol, and Isocyanide by Using Urea Hydrogen Peroxide in the Presence of Magnesium Bromide Catalyst

Document Type : Research Article

Authors
Ebrahim Soleimani
Tahereh Akbarpour
Mohammad Jafarzadeh
Department of Chemistry, Razi University, Kermanshah, I.R. IRAN
Abstract
A three-component reaction between the derivatives of benzyl alcohol, 2-aminophenol, and isocyanide for preparation Benzo[b][1,4]oxazine-2-amine derivatives has been reported. In this reaction, benzaldehyde derivatives were obtained as in situ from benzyl alcohol under oxidation by in urea hydrogen peroxide and magnesium bromide catalyst. This reaction was preferred in High efficiency and easy separation products of the reaction conditions. 
Keywords
2-amino phenol
Benzoxazine
Benzyl alcohol
Benzaldehyde
Isocyanide

Subjects

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