Nashrieh Shimi va Mohandesi Shimi Iran

Nashrieh Shimi va Mohandesi Shimi Iran

Magnetic Raffinose Nanocomposite: A Green Catalyst for the Synthesis of 2-amino-3-cyano-4H-pyran Derivatives

Document Type : Research Article

Authors
Ali Maleki
Fereshteh Hassanzadeh Afruzi
Mir Saeed Esmaeili
Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, I.R. IRAN
Abstract
In this study, 2-amino-3-cyano-4H-pyran derivatives were prepared through the three‐component condensation reaction between dimedone, aromatic aldehydes, and malononitrile in the presence of magnetic raffinose nanocomposite as green, biocompatible, and heterogeneous catalyst. The desired products were achieved within 10-30 minutes with yields of 80-95 percent. Synthetic nanocomposite has been characterized by conventional methods including Fourier Transforms InfraRed (FT‐IR) spectroscopy, Energy Dispersive X-ray (EDX) analysis, Scanning Electron Microscopy (SEM) images, Field Emission Scanning Electron Microscopy (FESEM), Vibrating Sample Magnetometer (VSM), and X-Ray Diffraction (XRD) pattern. This protocol has advantages such as mild conditions, short reaction times, simple procedure, excellent yields of the products, and purification of the products by chromatography-free methods. The magnetic properties of the nanocomposite caused its easy separation by using the external magnetic field from the reaction mixture then the catalyst was reused at least five times without a significant decrease in its catalytic activity.
Keywords
Green catalyst
Raffinose
Magnetic nanocomposite
2-amino-3-cyano-4H-pyran
Multicomponent reaction

Subjects

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