Nashrieh Shimi va Mohandesi Shimi Iran

Nashrieh Shimi va Mohandesi Shimi Iran

Synthesis of Benzylidene Bis(4-Hydroxycoumarin) Derivatives Using a Polymer Nanocomposite

Document Type : Research Article

Authors
Mohammadreza Nazarifar
Ghasem Rahpaima
Jalil Khezri
Department of Chemistry, Lamerd Branch, Islamic Azad University, Lamerd, I.R. IRAN
Abstract
In this study, polymer nanocomposites based on 2-aminophenol and Palm date have been introduced as an efficient and inexpensive catalyst and successfully used for the synthesis of benzylidene Bis(4-Hydroxycoumarin) derivatives. The polymer and nanocomposite were characterized by a Scanning Electron Microscope (SEM). Benzylidene Bis(4-Hydroxycoumarin) Derivatives have recently attracted much attention as an important class of heterocycles to their useful biological and pharmacological properties, herein we report a novel and efficient procedure for the synthesis of α,α′-benzylidenebis (4-hydroxycoumarin) derivatives based on the reaction of 4-hydroxycoumarin and aromatic aldehydes using polymer nanocomposites based on 2-aminophenol and Palm date as a solid heterogeneous catalyst in excellent yields (84-99%) and very short reaction time (2-5 min) in aqueous media (50%) have been described.
Keywords
Nanocomposite؛ 2-aminophenol
Palm date؛ 4-hydroxycoumarin؛ Aromatic Aldehydes
Subjects
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