عامل دار کردن حلقه های آروماتیک با حذف گروه نیترو از نیتروآرن ها

نوع مقاله : مروری

نویسندگان

گروه شیمی، دانشکده علوم پایه، دانشگاه هرمزگان، بندرعباس، ایران

چکیده

امروزه برای انجام هر واکنشی در شیمی آلی با واکنشگرهای گوناگونی مواجه می­شویم. هدف شیمیدانان، یافتن واکنشگرهای نوین و استفاده از روش­های نوین و سازگار با محیط زیست می­باشد. با توجه به­ این­که تاکنون سنتز ترکیب هایآلی با روش­ های گوناگون انجام شده است، به کارگیری یک روش سودمند با واکنشگرهای ارزان، غیرسمی و گزینش­پذیر، با پایداری بالا دارای اهمیت فراوانی می­ باشد. شیمیدانان به منظور یافتن الکتروفیل های آروماتیک مناسب تر در واکنش های جفت شدن متقاطع در مطالعه­ه ای اخیر خود بر ایجاد روشی جدید متمرکز شده­اند تا مشتق ­های نیتروآرن را به عنوان الکتروفیل مورد استفاده قرار دهند.در این مقاله مروری، کاربرد نیتروآرن­ها به عنوان الکتروفیل موثر در واکنش ­های جفت شدن متقاطع به منظور تشکیل پیوندهای کربن ـ کربن، کربن ـ گوگرد، کربن ـ اکسیژن و کربن ـ هیدروژن مطرح شده است.طبق پژوهش های صورت گرفته، این ترکیب­ ها در فرایند جفت شدن با نوکلئوفیل هایی مانند هترواتم ها و  نوکلئوفیل هایکربنی در حضور حلال ها، بازها و افزودنی های متفاوت در شرایط با فلز یا بدون فلز قرار گرفته­ اند و به این ترتیب پیوندهای کربن ـ کربن، کربن ـ نیتروژن،کربن ـ اکسیژن، کربن ـ  هیدروژن و کربن ـ گوگرد تشکیل شده است.

کلیدواژه‌ها

موضوعات


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