Nashrieh Shimi va Mohandesi Shimi Iran

Nashrieh Shimi va Mohandesi Shimi Iran

Synthesis, Characterization, and Biological Properties of Cu(II) Mixed-Lgand Complexes Incorporating Asymmetric Schiff Base Ligands

Document Type : Research Article

Authors
Fatemeh Khajoee Nejad
Mehrji Khosravan
Yousef Ebrahimipour
Department of Chemistry, Faculty of Science, Shahid Bahonar University of Kerman, Kerman, I.R. IRAN
Abstract
In this research, two tridentate Schiff base ligands 3-((2‐hydroxy‐3 methoxybenzylidene) amino)-2-methylquinazolin-4(3H)-one [HL1] and 3-((5-bromo-2-hydroxy-3-methoxybenzylidene)amino)-2-methylquinazolin-4(3H)-one [HL2] and their mixed-ligand complexes [Cu(L1)(bipy)] and [Cu(L2)(bipy)]; (bipy=2,2 bipyridine) were synthesized and fully characterized using spectroscopic techniques such as FT-IR, UV-Vis, and mass spectroscopy techniques. The element analysis, molar conductivity and melting points of these compounds were also determined. Antibacterial activities of the ligands and Cu(II) complexes were evaluated against Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa. According to the results, complexes showed significantly higher antibacterial activities compared to their related ligands
Keywords
Schiffbase
Cu(II) complex
spectral technique
antibacterial activity

Subjects

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