Investigation on Acting Mechanism of Nitrogen Source in Culture on Medium pH and Production of Poly-gamma-glutamate byFlavobacterium sp.

Document Type : Research Article

Authors

1 Institute of Biotechnology Science and Technology, Malek Ashtar University of Technology, Tehran, I.R. IRAN

2 Yong Researchers and Elites Club, North Tehran Branch, Islamic Azad University, Tehran, I.R. IRAN

Abstract

 Poly-Gamma-glutamate, biopolymer polyamide is consisting of units glutamic acid, that due to biodegradability and non-toxicity property as a biological compound can be used in many fields such as medical and pharmaceutical, food, hydrogels, flocculants, moisture absorbers, thickener and drug carriers and anti-corrosion coatings. Therefore, have been done extensive studies to the over efficiency production of the biopolymer. That is why in this study was evaluated the effect of the concentration of nitrogen source as an important nutritional source on the pH and cell growth, then was studied in terms of how and through what mechanism the production of species flavobacterium gamma glutamate made an impact and Finally, in order to optimize the nitrogen source evaluated five different nitrogen source and sodium glutamate with the highest yields

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