Nashrieh Shimi va Mohandesi Shimi Iran

Nashrieh Shimi va Mohandesi Shimi Iran

Sensitive Determination of Aflatoxin B1 Using Fluorescence of ZnO Quantum Dots-Molecularly Imprinted Polymer Composite

Document Type : Research Article

Author
Behrouz Vahid
Department of Chemical Engineering, Tabriz Branch, Islamic Azad University, Tabriz, Iran
Abstract
Molecularly Imprinting Polymer (MIP)-coated A ZnO Quantum Dots (QDs) composite was introduced for selective determination of Aflatoxin B1 (AFB) as a template. The MIP layer was obtained by a simple method containing the self-assembly process of 3-aminopropyl triethoxysilane (APTES) monomers and tetraethyl ortho-silicate as a cross-linking agent. In order to create suitable sites in the polymeric matrix, AFB was applied as a proper template molecule. The inherent advantage of the MIP procedure is the great tendency of the prepared QDs toward the AFB molecules. The MIP-coated ZnO QDs displayed a potent fluorescence emission which could be quenched in the presence of AFB. This effect was exploited as the basis of a selective probe for the detection of AFB some water samples. In optimal conditions, a linear relationship between the emission intensity of prepared composite and concentration of AFB was obtained in the range of 0.008-1 mg/L with a detection limit of 0.003 mg/L. Linking the high selectivity of the MIP component with individual fluorescence features of ZnO QDs offers a sensitive and selective method for recognizing various toxic detection. The established method was satisfactorily applied for the determination of AFB contamination in environmental water samples.
Keywords
ZnO quantum dots
Molecularly imprintثی polymer
Composite
Aflatoxin B1
Fluorescence

Subjects

[1] López G., José S., Frenich A. G., Vidal J.L.M., Romero‐González R., Determination of Aflatoxins B1, B2, G1, G2 and Ochratoxin A in Animal feed by Ultra-High‐Performance Liquid Chromatography–Tandem mass Spectrometry, J. Sep. Sci., 33(4‐5): 502-508 (2010).
[2] Halil T., Arslan R., Determination of Aflatoxin B1 Levels in Organic Spices and Herbs, Sci. World J., 2013: 874093 (2013).
[3] Ghali, R., Belouaer, I., Hdiri, S., Ghorbel, H., Maaroufi, K., Hedilli A., Simultaneous HPLC Determination of Aflatoxins B1, B2, G1 and G2 in Tunisian Sorghum and Pistachios, J. Food Comp. Anal., 22(7): 751-755 (2009).
[4] Arranz I., Stroka J., Neugebauer M.I.C.H.A.E.L., Determination of Aflatoxin B1 in Tiger Nut-Based Soft Drinks, Food Add. Contamin., 23: 305-308 (2006).
[5] Bavili Tabrizi A., Panahi M., Solid Phase Extraction Using Modified Magnetic Iron Oxide Nanoparticles for Extraction and Spectrofluorimetric Determination of Carvedilol in Human Plasma Samples, Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 36(3): 115-125 (2017).
[6] مهرنوش شه دوست خانی؛ ژیلا آزاد؛ کاظم کارگش، مطالعه رفتار کمپلکس های آهن (III) و کبالت (II) استیل استونیت در حلال های آلی با استفاده از روش های فلوئورسانس و اسپکترومتری فرابنفش ـ مرئی، نشریه شیمی و مهندسی شیمی ایران، (3)36: 83 تا 91 (1396).
[7] Cui L., He X.P., Chen G.R., Recent Progress in Quantum Dot Based Sensors, Rsc Adv., 5: 26644-26663 (2015).
[8] Ren X., Chen L., Preparation of Molecularly Imprinted Polymer Coated Quantum Dots to Detect Nicosulfuron in Water Samples, Anal. Bioanal. Chem., 407: 8087-8095 (2015).
[9] Xu S.F., Lu H.Z., Li J.H., Song X.L., Wang A.X., Chen L.X., Han S.B., Dummy Molecularly Imprinted Polymers-Capped CdTe Quantum Dots for the Fluorescent Sensing of 2,4,6-Trinitrotoluene, Appl. Mater. Interfaces, 5: 8146–8154 (2013).
[10] Zhang Z., Li J.H., Wang X.Y., Shen D.Z., Chen L.X., Quantum Dots Based Mesoporous Structured Imprinting Microspheres for the Sensitive Fluorescent Detection of Phycocyanin, Appl. Mater. Interfaces, 7: 9118–9127 (2015).
[11] Hagura N., Ogi T., Shirahama T., Iskandar F., Okuyama K., Highly Luminescent Silica-Coated ZnO Nanoparticles Dispersed in an Aqueous Medium, J. Lumin., 131: 921-925 (2011).
[12] Fonoberov V.A., Alim K.A., Balandin A.A., Xiu F., Liu J., Photoluminescence Investigation of the Carrier Recombination Processes in ZnO Quantum Dots and Nanocrystals, Phy. Rev. B, 73: 165317 (2006).
[13] Segets D., Gradl J., Taylor R. K., Vassilev V., Peukert W., Analysis of Optical Absorbance Spectra for the Determination of ZnO Nanoparticle Size Distribution, Solubility, and Surface Energy, ACS Nano, 3: 1703-1710 (2009).
[14] Asok A., Gandhi M. N., Kulkarni A. R., Enhanced Visible Photoluminescence in ZnO Quantum Dots by Promotion of Oxygen Vacancy Formation, Nanoscale, 4: 4943-4946 (2012).
[15] Xu X., Xu C., Shi Z., Yang C., Yu B., Hu J., Identification of Visible Emission from ZnO Quantum Dots: Excitation-Dependence and Size-Dependence, J. Appl. Phy., 111: 083521 (2012).
[16] Zhao D., Song H., Hao L., Liu X., Zhang L., Lv Y., Luminescent ZnO Quantum Dots for Sensitive and Selective Detection of Dopamine, Talanta, 107: 133-139 (2013).
[17] Fonoberov V.A., Balandin A.A., Origin of Ultraviolet Photoluminescence in ZnO Quantum Dots: Confined Excitons Versus Surface-Bound Impurity Exciton Complexes, App. Phy. Lett., 85: 5971-5973 (2004).
[18] Patra M. K., Manoth M., Singh V. K., Gowd G. S., Choudhry V. S., Vadera S. R., Kumar N., Synthesis of Stable Dispersion of ZnO Quantum Dots in Aqueous Medium Showing Visible Emission from Bluish Green to Yellow, J. Lumin., 129: 320-324 (2009).
[19] Ren X., Chen L., Quantum Dots Coated with Molecularly Imprinted Polymer as Fluorescence Probe for Detection of Cyphenothrin, Biosens. Bioelectron., 64: 182-188 (2015).
[20] Singh K., Mehta S. K., Luminescent ZnO Quantum Dots as an Efficient Sensor for Free Chlorine Detection in Water, Analyst, 141: 2487-2492 (2016).
[21] Chen L. X., Xu S.F., Li J.H., Recent Advances in Molecular Imprinting Technology: Current Status, Challenges and Highlighted Applications, Chem. Soc. Rev., 40: 2922–2942 (2011).
[22] Garcia R., Freitas A. M.C., Application of Molecularly Imprinted Polymers for the Analysis of Pesticide Residues in Food-A Highly Selective and Innovative Approach, Am. J. Anal. Chem., 2(8): 16-25 (2011).
[23] Bedwell T.S., Whitcombe M.J., Analytical Applications of MIPs in Diagnostic Assays: Future Perspectives, Anal. Bioanal. Chem., 408: 1735-1751 (2016).
[24] Tang J., Xiang L., Development of a Probe Based on Quantum Dots Embedded with Molecularly Imprinted Polymers to Detect Parathion, Pol. J. Environ. Stud., 25: 787-793 (2016).
[25] Abbasifar J., Samadi-Maybodi A., Selective Determination of Atropine Using poly Dopamine-Coated Molecularly Imprinted Mn-Doped ZnS Quantum Dots, J. Fluoresc., 26: 1645-1652 (2016).
[26] Huy B.T., Seo M.H., Zhang X., Lee Y.I., Selective Optosensing of Clenbuterol and Melamine Using Molecularly Imprinted Polymer-Capped CdTe Quantum Dots, Biosens. Bioelectron., 57: 310-316 (2014).
[27] Chantada-Vázquez M.P., Sánchez-González J., Peña-Vázquez E., Tabernero M. J., Bermejo A.M., Bermejo-Barrera P., Moreda-Piñeiro A., Synthesis and Characterization of Novel Molecularly Imprinted Polymer–Coated Mn-Doped ZnS Quantum Dots for Specific Fluorescent Recognition of Cocaine, Biosens. Bioelectron., 75: 213-221 (2016).
[28] Amjadi M., Jalili R., Manzoori J. L., A Sensitive Fluorescent Nanosensor for Chloramphenicol Based on Molecularly Imprinted Polymer‐Capped CdTe Quantum Dots, Luminescence, 31: 633–639 (2015).
[29] Ge S., Lu J., Ge L., Yan M., Yu J., Development of a Novel Deltamethrin Sensor Based on Molecularly Imprinted Silica Nanospheres Embedded CdTe Quantum Dots, Spectrochim. Acta A, 79: 1704-1709 (2011).
[30] Liu J., Chen H., Lin Z., Lin, J. M., Preparation of Surface Imprinting Polymer Capped Mn-Doped ZnS Quantum Dots and Their Application for Chemiluminescence Detection of 4-Nitrophenol in Tap Water, Anal. Chem., 82: 7380-7386 (2010).
[31] Wei F., Wu Y., Xu G., Gao Y., Yang J., Liu L., Zhou P., Hu Q., Molecularly Imprinted Polymer Based on CdTe@ SiO2 Quantum Dots as a Fluorescent Sensor for the Recognition of Norepinephrine, Analyst, 139: 5785-5792 (2014).
[32] Wang H.F., He Y., JiT R., Yan X.P., Surface Molecular Imprinting on Mn-Doped ZnS Quantum Dots for Room-Temperature Phosphorescence Optosensing of Pentachlorophenol in Water, Anal. Chem., 81: 1615-1621 (2009).
[33] Zhang W., He X. W., Chen Y., Li W. Y., Zhang Y. K., Composite of CdTe Quantum Dots and Molecularly Imprinted Polymer as a Sensing Material for Cytochrome c. Biosens. Bioelectron., 26: 2553-2558 (2011).
[34] Zhao Y., Ma Y., Li H., Wang L., Composite QDs@MIP Nanospheres for Specific Recognition and Direct Fluorescent Quantification of Pesticides in Aqueous Media, Anal., Chem., 84: 386-395 (2011).
[35] Singh K., Chaudhary G.R., Singh S., Mehta S.K., Synthesis of Highly Luminescent Water Stable ZnO Quantum Dots as Photoluminescent Sensor for Picric Acid, J. Lumin., 154: 148-154 (2014).
[36] Rahman I. A., Padavettan, V., Synthesis of Silica Nanoparticles by Sol-Gel: Size-Dependent Properties, Surface Modification, and Applications in Silica-Polymer Nanocomposites- A Review, J. Nanomater., 2012: 8 (2012).
[37] Lecoq, E., Duday, D., Bulou, S., Frache, G., Hilt, F., Maurau, R., Choquet, P., Plasma Polymerization of APTES to Elaborate Nitrogen Containing Organosilicon Thin Films: Influence of Process Parameters and Discussion about the Growing Mechanisms, Plasma Process. Polym., 10: 250-261 (2013).
[38] Amiri, A., Ramazani, A., Jahanshahi, M., Moghadamnia, A., Synthesis and Evaluating of Nanoporous Molecularly Imprinted Polymers for Extraction of Quercetin as a Bioactive Component of Medicinal Plants, Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 35: 11-19 (2016).