Multi-Component Synthesis of Xanthene Derivatives Using Tannic Acid and Alginic Acid as a Natural Catalyst

Document Type : Research Article


Department of Medicinal Plants Production, University of Nahavand, Nahavand, I.R. IRAN


In this work, tannic acid and aliginic acid as highly efficient catalysts were applied for the one-pot multicomponent synthesis of  9- Aryl-1,8-dioxo-octahydro- xanthene, 14-Aryl-14H- dibenzo[a,j] xanthene, 9,9- dimethyl-12-Aryl-8,9,10,12,tetrahydro-benzo[a]xanthene derivatives under the neutral and solvent-free conditions. These natural biopolymeric heterogeneous catalysts encompass advantages such as they are cheap and biodegradable and the protocols avoid using the expensive catalyst and toxic solvent. We believe that this methodology is simple, high yielding an efficient, time-saving, and environmentally friendly. In addition, this method is superior to reported methods in the literature, for the synthesis of various xanthene derivatives.


Main Subjects

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