Determination and Study of Propranolol on Carbon Paste Electrode Modified with Chitosan Grafting by Glutaraldehyde Magnetic Nanoparticles

Document Type : Research Article


1 Department of Chemistry, Faculty of Science, University of Birjand, Birjand, I.R. IRAN

2 Department of Chemistry, Faculty of Basic Sciences, Shahid Chamran University of Ahvaz, Ahvaz, I.R. IRAN


In this research, electrochemical measurement of propranolol drug on carbon paste electrode modified with chitosan grafting by glutaraldehyde magnetic nanoparticles was studied. Cyclic voltammetry and square wave voltammetry Techniques were used to study the drug. In order to characterize the modifier, FT-IR, XRD, SEM, EDX, and BET analysis were used. The effective factors on the performance of the electrode were investigated and optimum conditions were obtained as follows: pH = 7, absorption time of 10 minutes, and the amount of 10% modifier. At the optimum conditions, the dynamic linear range of propranolol was 1 to 14 μM and 14 to 284 μM and the detection limit was 0.3 μM. This electrode was investigated to measure propranolol in real samples. Compared to other measurement methods, ease of operation and reasonable price, without losing the detection limit, are other features of this electrode.


Main Subjects

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