Ag-Nanowire Diffusion into the Carbon Nanotube: an Efficient Method for Anti-Cancer Drug Release

Akbarzadeh, Hamed; Mehrjouei, Esmat; Abbaspour, Mohsen; Mohsen; Salemi, Sirous

Ag-Nanowire Diffusion into the Carbon Nanotube: an Efficient Method for Anti-Cancer Drug Release

Document Type : Research Article

Authors

Department of Chemistry, Hakim Sabzevari University, Sabzevar, I.R. IRAN

Abstract

In this study, release mechanism of cisplatin anti-cancer drug inside Single-Walled Carbon NanoTube (SWCNT) through Ag-nanowire diffusion and also, the effects of nanotube diameter and temperature on the rate of release process was investigated via Molecular Dynamics (MD) simulation. The results showed that the van der Waals interaction between the Ag-nanowire and the SWCNT act as the driving force for the drug release which the highest of the release rate of cisplatin was observed in the body temperature and in the SWCNT with a larger diameter. Finally, the kinetics of drug release is fast and not related to the structural parameters of the nanotube and temperature, significantly

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References

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