Nashrieh Shimi va Mohandesi Shimi Iran

Nashrieh Shimi va Mohandesi Shimi Iran

Preparation and Characterization of a New Silver/ Starch – Poly(diphenylsulfonyl phthalate) Nanocomposite and Study of Its Drug Releasing

Document Type : Research Article

Authors
Hooshang Hamidian 1
Somayeh Alibigi 1
Tayebeh Tavakoli 1
Samieh Fozooni 2
1 Department of Chemistry, Payame Noor University (PNU), Tehran, I. R. IRAN
2 Department of Chemistry, Faculty of Science, Shahid Bahonar University of Kerman, Kerman, I.R. IRAN
Abstract
Today, polymer-based nanocomposites are used in medicine and drug delivery  Non-toxic and environmentally friendly nanocomposites are very important. In this study, new polyester-based nanocomposites were prepared using silver nanoparticles, starch, and poly(diphenylsulfonyl phthalate). The structure and morphology of the new nanocomposite were investigated using FT-IR, XRD, DLS, and FE- SEM. Swelling and drug release of the new nanocomposite were determined based on different amounts of silver nanoparticles. A polymeric alloy of starch and poly(diphenylsulfonyl phthalate) had the highest swelling. Drug loading and release in nanocomposites decreased approximately with the increasing amount of silver nanoparticles.
Keywords
Nanocomposite
Starch
Poly(diphenyl sulfonyl phthalate)
Silver nanoparticles
Drug delivery
Subjects
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