An efficient and sustainable procedure for the synthesis of amidoalkyl naphthols under solvent-free conditions using a novel graphene oxide based catalyst functionalized with 2-aminobenzothiazole and phosphoric acid

Document Type : Research Article


1 Department of Basic Science, Faculty of chemistry, Payame Noor University, PO BOX 19395-3697 Tehran, Iran.

2 Department of Basic Science, Faculty of Chemistry, Payame Noor University (PNU), PO BOX 19395-3697 Tehran, Iran.

3 Department of Basic Science, Faculty of Chemistry, Payame Noor University, Tehran, Iran

4 Department of Basic Science - Faculty of Chemistry - Payame Noor University - Tehran - Iran


A highly efficient and sustainable procedure was described for the production of amidoalkylnaphthols using graphene oxide substituted 2-aminobenzothiazole which was activated by phosphoric acid (GO@ABTZ.H3PO4), catalyst. The catalyst was fully characterized by XRD, FT-IR, FE-SEM, TGA, and EDAX techniques. The synthesis was achieved using aldehydes, 2-naphthol, and acetamide (or urea) in the presence of catalyst through a one-pot three-component process without solvent. The best reaction condition, for 4-chlorobenzaldehyde derivative, involved the use of no solvent, 0.02g of the catalyst for 20 Min, at 70 °C and 95% yield. This eco-friendly catalyst managed to efficiently proceed organic synthesis processes. The proposed catalyst exhibited several advantages including cost-effectiveness, being non-metallic, providing green and environmentally-benign conditions, easy storage, facile handling, and durability. Moreover, the applied procedure has several priorities such as short reaction times, solvent-free conditions, simple work-up, and high yields. The stability and recoverability of the catalyst were also examined in five cycles which showed no considerable loss of activity.


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